Influence of Short-Term Dietary and Therapeutic Iodine Restriction on the Therapeutic Effects of Radioactive Iodine Therapy in Patients with Graves' Disease

Background: Several studies have investigated the factors affecting effects of radioactive iodine (131I) treatment (RAIT) in patients with Graves' disease. However, influence dietary or therapeutic on effect RAIT has not been fully elucidated yet. The aim this study was to investigate whether before influences a fixed-dose regimen and short-term restriction intake an iodine-sufficient area. Materials Methods: We retrospectively analyzed 81 Japanese disease treated following regimen: for 7 days as well discontinuation antithyroid drugs (ATDs), potassium (KI), both 5 RAIT. On day RAIT, we measured urinary content estimate daily intake. After adjusted dose ATDs, KI, according serum thyroid hormone levels every 1–2 months. Using data from these patients, at 1 year after were evaluated based necessity both. Results: Dietary weakly correlated 131I uptake (RAIU), but RAIU. strongly negatively associated estimated volume Neither nor affected association. Conclusion: This did find association between